SMALLER TANKS. OUTSIZED IMPACT.
Our technology de-risks the path to commercialization
for high volume, mainstream bio-products.
Our technology – hyper-fermentation – presents a fundamental transformation of the economics of biomanufacturing. We aim to solve
the gap in commercially viable manufacturing capacity, leveraging
hyper-fermentation to drive increased productivity, lower COGs,
and reduce capex and infrastructure requirements.
hyper-fermentation technology
After three decades of research, our team of scientists have solved the two key challenges which have historically prevented continuous fermentation from becoming mainstream. The challenges are:
Contamination
Unwanted microorganisms tend to infiltrate and grow in the ferment.
Genetic drift
The genetic make-up of the microorganism population changes over time which affects production of the
target product.
Proprietary ACE media
Fully defined media, with optimized nutrition to the microgram, designed to prevent contamination. The media recipes are specific to each micro-organism. Our library of ACE media recipes covers most common commercial organisms.
Hyper-Fermentation OS
Proprietary bioprocess and operating protocols that promotes genetic stability
and maximizes productivity. This continuous process operates like an assembly line for maximum efficiency and can be sustained over long periods of time.
The advantages
At Cauldron, our technology offers substantial advantages for precision fermentation companies targeting mainstream, high volume markets.
Compared to fed-batch methods, hyper-fermentation unlocks significant gains in productivity by solving historical continuous fermentation challenges to establish a scalable, repeatable continuous process. Our process allows us to harvest more frequently and at larger volumes vs. fed-batch fermentation.
of goods
Higher productivity drives significant reduction in manufacturing costs. Our smaller equipment uses less electricity and water compared to fed-batch fermentation. Because hyper-fermentation runs a continuous process, we have less frequent sterilization, driving down utilities costs. Fixed costs are also significantly reduced by lower labour costs and lower capex-dependent costs.
capital efficiency
Fed-batch fermentation requires scaling up to large tanks (300k-500kL vessels) to achieve economies of scale that can bring down the cost of manufacturing. These large vessels require significant capital deployment – over $100M in capex investment for a single mega-facility.
Hyper-fermentation’s productivity gains unlock smaller, more efficient capacity. Our process delivers over 5x more volume of product per dollar of capex compared to a 500kL fed-batch facility.
